Loxo Oncology (LOXO) is a biotech company built around the idea that cancer is best treated with highly targeted drugs paired to companion diagnostics. CEO Josh Bilenker, a partner at Aisling Capital, founded the company in 2013. Research and Development is outsourced, allowing about a dozen employees to manage company operations. Loxo acquired essentially all […]
September 9 Biotech Update
Well, there was certainly some additional news last night and I want to focus on that but it still seems like we are in a macro driven market with the current bias higher. It does feel, however, that macro is starting to move into the background but it remains to be seen if it will […]
A Quick look – XBI In The Decision Zone
SPDR S&P Biotech ETF (XBI) We will maintain our focus on the XBI as the biotech barometer. Noticing lately the fact XBI is outperforming the IBB & the broader market SPY or SPX, might give us the sense that investors are again, willing to take more risk with the small-mid cap biotech companies after the […]
September 8 Biotech Update
I expected a more active Tuesday but perhaps all of the deals are taking a little longer to finalize. In fact, we have a pretty quiet morning which is going to once again push macro into the forefront (which at least appears to be good this morning but we usually see these opening moves fade). […]
September 2 Biotech Update
The market looks bad again. Even though we are having a mini rally this morning, the sellers appear to be in control so far this week. I still think China is a red herring and the market is pricing in a Fed rate hike and the potential the risk that it starts a deflationary spiral. […]
Trevena Scores In Pain Study
Trevena Inc. (TRVN) presented positive Phase 2b results Monday August 31 from its TRV130 pain study. The primary endpoint of superior pain reduction compared to placebo was met, as well as superiority to morphine in the secondary endpoint of lower rates of nausea, vomiting, and hypoventilation. The results were quite good, and together with the previous […]
ESPR Quick Note
Esperion shares have fallen over 8% today as The Medicines Co and Alnylam released early data on their RNAi candidate, ALN-PCSsc, targeting PCSK9. The drug was shown to efficiently and safely reduce LCL-C when given subcutaneously. It was shown to maintain LCL-C suppression 140 days after a single 1.5 ml injection. The long duration of […]
August 31 Biotech Update
Looks like a slightly lower start to the week. Macro still obviously matters but the size of the moves seems to be decreasing. I find it interesting that the weakness comes after Fisher had a relatively hawkish Fed talk at Jackson Hole, where he noted that the Fed could raise rates before they saw inflation. […]
August 28 Biotech Update
I was busy for a day and the market does great but I come back and we have a gap lower. Sorry. In all seriousness, however, the snap back rally needs to pause but given the sell-off, I think we need to see the market shake off the gap lower and end higher today. We […]
August 26 Biotech Update
The market had a rough day yesterday where the rally from the “lows” earlier in the week faded at the end of the day. That is never a good sign and at this point we need to ignore the gaps higher until they strengthen into the end of the day as opposed to fade. I […]
August 25 Biotech Update
Despite ending the day down significantly, it actually felt like a good day. I wanted to post a real quick and short note as from now on Tuesday and Thursday are going to be quite busy. So I will try to post on those days if possible but do not be surprised if nothing comes […]
August 24 Biotech Update
Wow. What a start to the week. In terms of news there was not much but we had an incredible flash crash in the large caps at the open. From a technical perspective, I do not know if this signals an end or what but there were some great long term bargains that I missed […]
August 21 Biotech Update
So it is obviously getting rough and we got our first peeks of panic yesterday. Most everyone seems to think that the worst is yet to come and I would not be surprised to see even more downside but obviously the contrarian in me wants to move to the other side of the boat when […]
August 20 Biotech Update
Another gap lower but the market remains in a rut refusing to breakdown or breakout. As I have said before, 2015 has been a year of churn and that is going to end up being really robust support for a breakout or really strong resistance for a breakdown. At this point, there is not a […]
August 19 Biotech Update
Not much has changed sector wide since I last wrote but we did have a trade play out, although not quite the way I expected. I want to talk about it today both because there have been some questions around it but also because it goes to the larger theme I think is at work […]
August 14 Biotech Update
We had the continuation yesterday only to fail later in the day. It is looking that this bounce might only be setting up another leg lower but it is clearly too early to have any confidence. That being said I would at least be prepared in case there is another leg lower as it would […]
August 13 Biotech Update
We had our reversal yesterday that I talked about, although I had my doubts for a little while. That is probably enough to get some buying interest barring additional negative macro issues. China did a third round of devaluations but I suspect it will have less of an effect on the market given it is […]
August 12 Biotech Update
Essentially more of the same yesterday and into the morning today. At the very least, I think we are probably close to a bounce and would not be surprised to see a gap lower this morning and then a rally into the green by the end of the day. It is amazing that the market […]
August 11 Biotech Update
Not a lot of biotech news again but macro is creeping back into the discussion with China devaluing their currency. Who knows the pin action this will have on the sector as it could mean global growth is too slow and biotechs are then the best growers. It could mean that it will trigger more […]
August 10 Biotech Update
We are getting a spurt of IO collaborations this morning but no major news or M&A. After the sell off Friday (and come back), I would not be surprised to see that positive momentum continue this morning. Worst case scenario would be early strength and then faded all day. Best case, obviously, would be early […]
